Cayman Chemical

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FABP4 Protein and Assays

4E-BP1 EIA Kits

His-Express Detection EIA Kit

8-hydroxy-2-deoxy Guanosine EIA Kit

Apoptotic Blebs Assay Kit

SIRT1 (human recombinant)

SIRT3 (human recombinant)

LSD1 Inhibitor Screening Assay Kit

p53 Transcription Factor Assay Kit

KRP 203

New Products

5-OxoETE Lipid Maps MS Standard

Prostaglandin J2 Lipid Maps MS Standard

Pyrimidine-4-carboxylic Acid

15-keto Prostaglandin F2α Lipid Maps MS Standard

17(R)-Resolvin D1

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FABP4 Protein and Assays

FABP4—a new therapeutic target for obesity and diabetes

Cayman Chemical is a leading provider of high-purity, active Fatty Acid Binding Proteins. Contact our sales staff for quotations on bulk preparations of FABP4 and FABP4 assay kits for your drug discovery efforts.

All FABP4 products from Cayman Chemical…

4E-BP1 EIA Kits

4E-BP1—a key regulator of protein translation

Cayman's two new immunometric (i.e., sandwich) assays are designed to accurately detect human Phospho-Thr³⁷/Thr⁴⁶ 4E-BP1 and total 4E-BP1 in cell culture lysates.

Full information for 4E-BP1 EIA Kits...

His-Express Detection EIA Kit

• For the rapid screening of His-tagged recombinant proteins in cell lysates and affinity column fractions

• Use in place of SDS-PAGE for semi-quantitative results in just a few hours

Full information for His-Express Detection Kits...

05-21 · 8-hydroxy-2-deoxy Guanosine EIA Kit

A competitive EIA for quantification of 8-OH-2dG

Cayman’s 8-OH-dG EIA is a competitive assay that can be used for the quantification of 8-OH-dG in urine, cell culture, plasma, and other sample matrices. The EIA utilizes an anti-mouse IgG-coated plate and a tracer consisting of an 8-OH-dG-enzyme conjugate. This …

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02-29 · Apoptotic Blebs Assay Kit

Cayman’s Apoptotic Blebs Assay Kit employs a recombinant protein containing single-chain variable fragments (scFv) of D56R fused to the protein A domain B fraction as an antibody for apoptotic blebs. The protein A portion of this fusion protein is recognized and visualized by fluorescein-conjugated …

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09-24 · SIRT1 (human recombinant) New

Source: recombinant N-terminal GST-tagged SIRT1 amino acids 193-747 purified from E. coli · M_r: 89.2 kDa ·

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12-15 · SIRT3 (human recombinant) New

Source: recombinant N-terminal Hexahistidine-tagged SIRT3 amino acids 101-399 purified from E. coli · M_r: 33.5 kDa ·

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10-16 · LSD1 Inhibitor Screening Assay Kit New

A convenient fluorescence-based method for screening LSD1-specific inhibitors

Cayman’s LSD1 Inhibitor Screening Assay Kit provides a convenient fluorescence-based method for screening LSD1-specific inhibitors. The assay is based on the multistep enzymatic reaction in which LSD1 first produces H₂O₂ during the demethylation of lysine 4 on a peptide …

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10-27 · p53 Transcription Factor Assay Kit New

96-Well assay for measurement of p53

Cayman’s p53 Transcription Factor Assay is a non-radioactive, sensitive method for detecting specific transcription factor DNA binding activity in nuclear extracts. A specific-double stranded DNA (dsDNA) sequence containing the p53 response element is immobilized onto the wells of a 96-well plate. …

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10-29 · KRP 203 New Excl.

An immune modulator that is a selective S1P₁ receptor agonist

KRP 203 is a selective S1P₁ receptor agonist that has been shown to reduce peripheral lymphocyte infiltration and to prolong survival in rat transplant models. The phosphorylated form of KRP 203 demonstrates a high affinity for the S1P₁ receptor with an ED₅₀ value in the nM range and …

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01-05 · 5-OxoETE Lipid Maps MS Standard New

Designed for the convenient, precise quantification of 5-OxoETE

5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils by a specific dehydrogenase. It stimulates cytosolic calcium levels in neutrophils with an EC₅₀ value of 2 nM. 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and …

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01-05 · Prostaglandin J₂ Lipid Maps MS Standard New

Designed for the convenient, precise quantification of Prostaglandin J₂

Prostaglandin J₂ (PGJ₂) is formed from PGD₂ by the elimination of the C-9 hydroxyl group, a process which is accelerated by the presence of albumin. PGJ₂ inhibits platelet aggregation with an IC₅₀ of about 5-10 nM. PGJ₂ has antimitotic and …

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01-05 · Pyrimidine-4-carboxylic Acid New

Synthetic intermediate

Pyrimidine-4-carboxylic acid is a synthetic intermediate useful for pharmaceutical synthesis.

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12-18 · 15-keto Prostaglandin F_2α Lipid Maps MS Standard New

Designed for the convenient, precise quantification of 15-keto Prostaglandin F_2α

15-keto Prostaglandin F_2α (15-keto PGF_2α) is the first metabolite of PGF_2α. in the 15-hydroxy PGDH pathway. It is one of the critical components in the goldfish and Atlantic salmon postovulatory pheromone. 15-keto PGF_2α stimulates the male goldfish …

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12-18 · 17(R)-Resolvin D1 New Excl.

A potent anti-inflammatory lipid mediator

17(R)-Resolvin D1 is an aspirin-triggered epimer of resolvin D1 that reduces human polymorphonuclear leukocyte (PMN) transendothelial migration, the earliest event in acute inflammation, with equipotency to resolvin D1 (EC₅₀ ~30 nM). 17(R)-Resolvin D1 exhibits a dose-dependent …

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